import org.codehaus.jettison.json.JSONObject; //导入方法依赖的package包/类

public List getVariantsGA4GH(final String callSetId, final String start, final String end,

final String chrName) throws Ga4ghResourceUnavailableException {

final ArrayList listCallSetId = new ArrayList<>();

VariantsSearch referenceBasesEntity = null;

final List resultVariantSearch = new ArrayList<>();

final JSONObject jsonObject = new JSONObject();

final String variantSetId;

final int index = callSetId.indexOf('-');

if (index <= 0) {

listCallSetId.add(callSetId + "-0");

variantSetId = callSetId;

} else {

listCallSetId.add(callSetId);

variantSetId = callSetId.substring(0, index);

}

try {

jsonObject.put(Constants.CALL_SET_ID, listCallSetId);

jsonObject.put(Constants.END_POSITION, end);

jsonObject.put(Constants.START_POSITION, start);

jsonObject.put(Constants.PAGE_SIZE, Constants.VARIANTS_PAGE_SIZE);

jsonObject.put(Constants.VARIANT_SET_ID, variantSetId);

jsonObject.put(Constants.REFERENCE_NAME, chrName);

jsonObject.put(Constants.PAGE_TOKEN, "");

final String location = Constants.URL_GOOGLE_GENOMIC_API +

Constants.URL_VARIANTS +

Constants.URL_SEARCH +

Constants.GOOGLE_API_KEY;

do {

if (referenceBasesEntity != null) {

jsonObject.remove(Constants.PAGE_TOKEN);

jsonObject.put(Constants.PAGE_TOKEN, referenceBasesEntity.getNextPageToken());

}

String geneData = httpDataManager.fetchData(location, jsonObject);

referenceBasesEntity = objectMapper.readValue(geneData, VariantsSearch.class);

resultVariantSearch.addAll(referenceBasesEntity.getVariants());

}

while (!referenceBasesEntity.getNextPageToken().isEmpty());

referenceBasesEntity.setVariants(resultVariantSearch);

} catch (IOException | JSONException | ExternalDbUnavailableException e) {

throw new Ga4ghResourceUnavailableException(callSetId, e);

}

return referenceBasesEntity.getVariants();

}